Jack Kerouac wrote two books about an alchemist, the first is Dr. Sax and the second (a posthumous publication) Dr. Sax and the Great World Snake. Kerouac was no alchemist himself but these books show it must have been a curiosity of his.

https://www.youtube.com/watch?v=z8waCKq9sxI

https://www.youtube.com/watch?v=rQcTXrptT5s